CROSS-SECTIONAL AND LONGITUDINAL GENOTYPE TO PHENOTYPE SURVEILLANCE OF SARS-COV-2 VARIANTS OVER THE FIRST FOUR YEARS OF THE COVID-19 PANDEMICRESEARCH IN CONTEXT

Summary: Background: Continued phenotyping and ongoing molecular epidemiology are important in current and future monitoring of emerging SARS-CoV-2 lineages.Herein we developed pragmatic strategies to track the emergence, spread and phenotype of SARS-CoV-2 variants in Australia in an era of decreasing diagnostic PCR testing and focused cohort-based

Recommender systems are widely used in e-commerce, news, and advertising, providing personalized recommendations by analyzing user interaction history.However, during large-scale data analysis and sharing, user privacy faces the risk of exposure, especially for users who wish to remain anonymous.While existing synthetic data methods perform well in

Data-as-a-Service (DaaS) is a branch of cloud computing that supports “querying the Web”.Due to its ultrahigh scale, it is essential to establish rules when defining resources’ costs and guidelines for infrastructure investments.Those decisions should prioritize minimizing the incidence of agreement breaches that compr

Feralization of genetically engineered (GE) crops increases the risk that transgenes will become integrated into natural and naturalizing plant populations.A key assumption of the management of GE crops is that populations of escaped plants are short-lived and therefore the risks they pose are limited.However, few populations of escaped crop plants

Programmed cell death is characterized by a cascade of tightly controlled events that culminate in the orchestrated death of the cell.In multicellular organisms autophagy and apoptosis are recognized as two principal means by which these genetically determined cell deaths occur.During plant-microbe interactions cell death programs can mediate both